Adult stem cell therapy
Stroke is the main cause of disability and death in the world within neurological diseases. The use of stem cells as a possible cell therapy in stroke has been tested for years. The results obtained from these studies, although conflicting or controversial in some aspects, are promising. In the last few years, the recent development of the induced pluripotent stem cells has opened new possibilities to find new cell therapies against stroke. In this review, we will provide an overview of the state of the art of cell therapy in stroke.
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Jump to navigation. An adult stem cell is thought to be an undifferentiated cell, found among differentiated cells in a tissue or organ. The adult stem cell can renew itself and can differentiate to yield some or all of the major specialized cell types of the tissue or organ. The primary roles of adult stem cells in a living organism are to maintain and repair the tissue in which they are found. Scientists also use the term somatic stem cell instead of adult stem cell, where somatic refers to cells of the body not the germ cells, sperm or eggs. Unlike embryonic stem cells , which are defined by their origin cells from the preimplantation -stage embryo , the origin of adult stem cells in some mature tissues is still under investigation. Research on adult stem cells has generated a great deal of excitement.
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The primary role of adult stem cells in humans is to maintain and repair the tissue in which they are found. Stem cells are very flexible cells, sometimes considered immature, that have not developed to a final specialized cell type like skin, liver, heart, etc. Since they have not yet specialized, stem cells can respond to different signals and needs in the body by becoming any of the various cell types needed, e. In that sense they are a bit like a maintenance crew that keeps repairing and replacing damaged or worn out cells in the body.
Adult stem cells are undifferentiated cells found throughout the body that divide to replenish dying cells and regenerate damaged tissues. Research into adult stem cells has been fueled by their abilities to divide or self-renew indefinitely and generate all the cell types of the organ from which they originate — potentially regenerating the entire organ from a few cells. Unlike embryonic stem cells, the use of adult stem cells in research and therapy is not controversial because the production of adult stem cells does not require the destruction of an embryo. The rigorous definition of a stem cell requires that it possesses two properties: Self-renewal - the ability to go through numerous cycles of cell division while maintaining the undifferentiated state.